Against the backdrop of contemporary urban development and cultural awareness, the need to enhance the distinctiveness of regional cultural characteristics and meet the spatial demands of modern commercial growth necessitates an integrated exploration in architectural design. This paper centers on how to effectively extract regional architectural color symbols and creatively integrate them into modern commercial building design, aiming to provide solutions for current challenges such as superficial cultural information translation, the difficulty in balancing cultural preservation with commercial viability, and the lack of systematic guidance in practical applications. The article establishes an objective color extraction pathway encompassing multi-source data collection, quantitative analysis and screening, and the generation of a thematic color spectrum library. Using the case study of the open-street design at Shanghai Shui On Panlong Tiandi, it demonstrates the practicality of integration strategies such as differentiated functional zoning guidance, modern light-and-shadow translation, and the construction of cultural narrative experiences. Ultimately, it forms a systematic methodological framework that balances cultural heritage expression with modern functional requirements.