Many children with autism have different sensory experience of the surrounding environment from ordinary people, and they are particularly sensitive to visual stimuli. Virtual reality (VR) technology can create a world where we can completely control the visual environment, which provides a more comfortable and safe healing space for autistic children. Therefore, this paper will discuss how to design the most suitable color matching scheme for autistic children in VR healing scenes, aiming at providing practical color matching suggestions for designing VR healing scenes that are really suitable for autistic children, make them feel comfortable and actively participate.