The research focuses on the impact of multimedia courseware color design on high school students' learning effectiveness, aims to clarify the specific relationship between the two, clarify the practical role of color design in high school students' learning process, and explore the effective path to optimize multimedia courseware color design, in order to provide practical reference for high school teachers to design multimedia courseware, help teachers use color elements more reasonably in courseware design, so that courseware can not only accurately transfer knowledge, but also help students maintain a good learning state through appropriate color design, so as to improve the quality of high school classroom teaching and promote the improvement of high school students' learning effectiveness.